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    CRO SERVICE AVAILABLE

    Electrophysiology based techniques

    Chronic Pain model

    Neuropathic pain, OA, Post-Operative,

    DPN, CIPN model

     

    Von frey filament test(Mechanical allodynia)

    Plantar test(Thermal hyperalgesia)

    Acute/Chronic Pain response analysis

    Electrophysiological study

    Human/Rodent DRG, Rodent Trigeminal ganglion neurons target candidate screen

    Cloned channels and receptors cell line assay

     

    Patch clamp recording

     - Resting membrane potential(RMP)

     - Rheobase

     - Spike threshold/Amplitude/Frequency

     - Ligand-gated/Voltage-gated ion channels

     - GPR Modulation

    Calcium imaging assay: IC50, EC50 analysis

    Disease Animal Efficacy Test

    Dry eye disease, Pain model

     

    Intraocular pressure, PRT test, Lissamine green staining

    CBC Etc.

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